Biohacking
Retatrutide hits three receptors and makes semaglutide and tirzepatide look like the warm-up act. The mechanism, the trial numbers, my dose and where I'm taking it next — and the one thing nobody warns you about: it works so well you'll stop eating protein and drinking water, and burn muscle.
Biohacking
TRT is the floor. Blast and cruise is what you do when the floor isn't enough — without the crashes. Sit at a maintenance dose, push to a supraphysiological one for a window, then drop back and hold. Where the line is, the timing, the ancillary stack, and the 250mg I aim for from a 100mg base.
Biohacking
BPC-157 and TB-500 — the "Wolverine Stack" — get sold as a comic-book healing serum. The reality is more useful: two repair peptides that keep you training when your tendons want to quit. What they do, what the evidence actually shows, and the bodybuilding reframe most write-ups miss.
AI
Anthropic spent two months telling the world Mythos was too dangerous to release. Friday at 5:21 PM, the US government took it literally — and export-controlled Fable 5 and Mythos 5 out of reach for every non-American on earth. It smells coordinated. It's worse: a prophecy Anthropic wrote itself.
Biohacking
I spent a long time treating carbohydrates as the enemy. Timing them around training instead became the best change I've made to my physique in a year — and somehow the fat is still coming off.
AI
Fable 5 is the first Mythos-class model the public can call — a tier above Opus, 1M context, double the price, and no zero-retention option. The catch: a safety classifier that automatically hands you back to Opus 4.8. Everything that actually matters.
AI
Anthropic's fourth Opus model in six months. The story isn't another point on SWE-bench, it's a model that flags its own broken code and a tool that lets one agent command hundreds. An honest scorecard from someone who runs agents all day.
Biohacking
Week 5 of the protocol, three updates: a NAD+ technique that finally works, an abdomen running out of real estate, and a primary-site switch to the lateral thigh.
AI
I handed a PR review to an agent. It silently created a follow-up ticket because the reviewer said "or". Welcome to prompt injection lite — and the same mechanism that, with a hostile reviewer, ends in your .env being curl'd to a stranger.
AI
xAI's terminal coding agent. Plan Mode by default, eight parallel subagents, Grok 4.3 Heavy under the hood, AGENTS.md / MCP / Skills compatible. The bets it makes, where to test them, and how to evaluate without religion.
AI
OpenAI shipped Codex inside the ChatGPT mobile app. Not a mobile IDE — a remote control surface for agent work. Pair once, supervise all your projects from the phone. The execution boundary is the product.
Biohacking
The NAD+ protocol moves to 100mg Wed-Sun AM: same 500mg weekly exposure, 60% lower per-session peak, cleaner timing, simpler hardware, and a monitoring window to prove it.
